The pregnancy estrogen Estetrol (E4) has a DUAL effect when treating heavily-pre-treated women with advanced breast cancer who have no further treatment options. First, E4 has an anti-tumor effect and second, E4 improves wellbeing.

The Dutch biotech company Pantarhei Oncology presents on December 13, 2019 at the San Antonio Breast Cancer Symposium (SABCS) in the USA the results of the first clinical study with High Doses of the fetal estrogen Estetrol (HDE4) in women with advanced end-stage breast cancer. Nine women without further treatment options participated in the study and were treated with 20, 40 or 60 mg E4 per day for 12 weeks. Anti-tumor effects after 12 weeks treatment were confirmed in 5 of 9 women and strong improvement of wellbeing occurred in 7 of 9 patients.

For more information please read the Press Release or the Poster.

Voor meer informatie lees hier het Nederlandstalig persbericht.

On Thursday October 17, 2019, Herjan Coelingh Bennink of Pantarhei Oncology lectured on: “Estetrol for the treatment of advanced breast cancer” in a symposium entitled “Breast cancer: new challenges in diagnosis, pathogenesis and therapy”. The symposium was chaired by Xiangyan Ruan and Kerstin Rhiem.

For more information, please read the abstract.

Contribution of Pantarhei Oncology to the 18th World Congress of the International Academy of the Human Reproduction (IAHR), April 3-6, 2019 in Dublin by an invited lecture of Herjan Coelingh Bennink.

On Thursday April 4, 2019, a key lecture entitled “Estrogens, Estetrol and Breast Cancer” was given by Herjan Coelingh Bennink, President of Pantarhei Oncology during a scientific session “Oncology, Breast and Gynecological Surgery”. The session was chaired by by Andrea Genazzani. For more information, please read the abstract.

Pantarhei Bioscience, the Dutch biopharmaceutical company, is pleased to announce the appointment of Yvette Zimmerman as Chief Executive Officer (CEO), with effect from January 2019. The founder of Pantarhei Herjan Coelingh Bennink speaks proudly about his successor: “Yvette is a very experienced drug developer and driven by what is really important for people and scientifically sound.”

During the 18 years of its existence, Pantarhei has filed more than 220 patents. Initially Pantarhei developed new medicines for Women’s Health. Following the foundation of the subsidiary company Pantarhei Oncology in 2014, the focus has been redirected to new treatment concepts for endocrine cancer, especially breast and prostate cancer.

Read more: Press Release New CEO Pantarhei Bioscience